High-Temperature Vacuum Stainless Steel Chemical Reactor

Extreme Thermal Range (-120°C to 300°C) | Precision Jacketed Synthesis | GMP Laboratory Grade


Engineered with a dual-layer precision design, this stainless steel reactor is a high-end system that integrates stirring, heating/cooling, reflux, and distillation. The internal vessel is designed for reaction solvents, while the jacketed layer allows for the circulation of thermal sources such as refrigerants, hot water, or thermal oil. This versatile chemical reactor supports both atmospheric and negative pressure (vacuum) stirring under airtight, constant-temperature conditions. It serves as a vacuum reactor or high-performance stainless steel autoclave for the chemical, pharmaceutical, and biotechnology research sectors.

Core Value Propositions


  • Extreme Temperature Versatility: Engineered to withstand extreme experimental conditions ranging from -120°C to 300°C. This unit serves as a high-performance “all-in-one” solution for both cryogenic synthesis and high-heat reactions.
  • Stable Vacuum Performance: Features a reinforced airtight structure and advanced mechanical seals. In a static state, it reliably maintains high vacuum levels, making it ideal for moisture-sensitive or low-boiling-point solvent recovery.
  • Intelligent VFD Stirring: Equipped with a variable frequency constant-speed system and digital display. This ensures uniform torque and smooth, consistent mixing even during high-viscosity chemical processes.
  • Premium Anti-Corrosion Setup: Outfitted with single or double-layer PTFE impellers and a zero-dead-space discharge valve. This configuration minimizes residue, prevents contamination, and extends the equipment’s service life.

Primary Application Scenarios


Advanced Chemical & Bio-R&D: The premier choice for research institutes performing specialized chemical synthesis, biological processing, and complex academic experiments.

Pharmaceutical Refining: Optimized for the extraction, purification, and high-vacuum concentration of sensitive herbal extracts or active pharmaceutical ingredients (APIs).

Fine Chemical Production: Facilitates precision constant-temperature stirring, reflux, and distillation within standardized industrial chemical workflows.

Food & Beverage Engineering: Meets strict industry hygiene requirements while providing the precise thermal control needed for food-grade material reactions.

Solutions to Critical Technical Challenges


  • Managing Wide Thermal Gaps: Unlike conventional reactors that fail at temperature extremes, our jacketed system supports a total range of 420°C, providing a single platform for diverse research.
  • Eliminating Batch Contamination: By utilizing a zero-dead-space discharge valve, the system ensures 100% material discharge and prevents liquid accumulation at the outlet.
  • Ensuring Vacuum Reliability: Precision-machined lid ports and mechanical seals prevent air leakage under negative pressure, ensuring the repeatability of high-vacuum experiments.
  • Resisting Aggressive Media: For acidic or alkaline reactions, the combination of a stainless steel vessel and PTFE-coated internals offers superior resistance compared to standard industrial mixers.
ModelSCF-1LSCF-2LSCF-3LSCF-5L
Reactor Capacity (L)1235
Jacket Capacity (L)11.51.52
MaterialSS304 Stainless Steel (SS316 Optional)
Thickness (mm)Inner Wall: 4mm, Outer Shell: 4mm (Customizable based on pressure)
Motor Power (kW)0.12
Stirring Speed (rpm)0-600
ControllerFrequency speed regulation; LCD digital display for temperature and speed
Voltage110V/220V, 50/60Hz
Vacuum Sealing0.098 MPa
Lid Ports (9 Total – Customizable)Stirrer Port: 32# Mechanical SealStirrer Port: 32# Mechanical Seal
Solid Feeding Port: φ45 Union with Sight GlassSolid Feeding Port: φ45 Union with Sight Glass
Temperature Port: φ12.7 Quick-opening ValveTemperature Port: φ19.7 Quick-opening Valve
Reflux Port: φ32.7 Quick-opening ValveReflux Port: φ38 Quick-opening Valve
Vent/Air Port: DN15 Ball ValveVent/Air Port: DN20 Ball Valve
Pressure Relief Port: φ32 UnionPressure Relief Port: φ32 Union
Nitrogen (N₂) Port: φ6mm Female ThreadNitrogen (N₂) Port: φ6mm Female Thread
Constant Pressure Funnel Port: φ12.7 Quick-opening ValveConstant Pressure Funnel Port: φ19 Quick-opening Valve
Pressure Gauge Port: φ8mm Female ThreadPressure Gauge Port: φ8mm Female Thread
Constant Pressure FunnelStainless Steel, 500ml
CondenserStainless Steel Serpentine (Coil) Condenser
Discharge ValveDN25 Ball ValveDN32 Ball Valve
PTFE Stirrerφ12 Anchor type (Other styles optional)
Support FrameSS304 Stainless Steel
Jacket Inlet/OutletDN15 Male Thread
Dimensions (mm)350×350×950350×350×1100500×400×1400600×500×1750
CustomizationNon-standard customization supported (Dimensions for reference only)
ModelSCF-10LSCF-20LSCF-30LSCF-50L
Reactor Capacity (L)10203050
Jacket Capacity (L)3.85815
MaterialSS304 Stainless Steel (SS316 Optional)
Thickness (mm)Inner Wall: 4mm, Outer Shell: 4mm (Customizable based on pressure)
Motor Power (kW)0.12
Stirring Speed (rpm)0-600
ControllerDigital frequency conversion speed control
Voltage110V/220V, 50/60Hz
Main Seal TypeSS304 Ceramic combination mechanical seal
Vessel Ports8 Ports (Optional/Customizable)
Vessel StructureDouble-layer Jacketed Stainless Steel
Working Pressure-0.1 MPa to 0.7 MPa
Stirring SealAdvanced PTFE mechanical seal
Stirrer TypePaddle type
Lid Ports (9 Total – Customizable)Stirrer Port: 32# Mechanical SealStirrer Port: 32# Mechanical Seal
Solid Feeding Port: φ51 Union with Sight GlassSolid Feeding Port: φ102 Union with Sight Glass
Temperature Port: φ12.7 Quick-opening ValveTemperature Port: φ19.7 Quick-opening Valve
Reflux Port: φ32 Quick-opening ValveReflux Port: φ38 Quick-opening Valve
Vent/Air Port: DN20 Ball ValveVent/Air Port: DN20 Ball Valve
Pressure Relief Port: φ32 UnionPressure Relief Port: φ32 Union
Nitrogen (N₂) Port: φ6mm Female ThreadNitrogen (N₂) Port: φ6mm Female Thread
Constant Pressure Funnel Port: φ12.7 Quick-opening ValveConstant Pressure Funnel Port: φ19 Quick-opening Valve
Pressure Gauge Port: M20×1.5 Female ThreadPressure Gauge Port: M20×1.5 Female Thread
Constant Pressure FunnelStainless Steel, 500ml
CondenserStainless Steel Serpentine (Coil) Condenser
Discharge ValveDN25 Ball ValveDN32 Ball Valve
PTFE Stirrerφ12 Anchor type (Other styles optional)
Jacket Inlet/OutletDN15 Male Thread
Optional UpgradesExplosion-proof Motor / SS316 Material / Heating Collection Flask / Electric Heating Jacket

Frequently Asked Questions


Answer: Absolutely. We specialize in providing tailored solutions. Depending on your material characteristics (such as viscosity, acidity, or heat sensitivity) and your facility’s requirements, we can customize the material grade (SS304 or SS316L), heating methods, mixing speeds, and vacuum levels to ensure optimal performance.

Answer: Quality is our top priority. Our equipment is manufactured in strict accordance with GMP and ISO standards. Before shipment, every unit undergoes rigorous testing, including hydraulic pressure tests, vacuum retention tests, and operational trials. We provide complete inspection reports and factory acceptance videos for your peace of mind.

Answer: We offer flexible heating configurations to suit your local energy resources:

Gas Heating: Ideal for facilities where gas is the most cost-effective energy source.

Electric Heating: Equipped with high-efficiency heating elements and precise temperature control.

Steam Heating: Designed with a high-pressure jacket for connection to an external boiler.

Answer: Yes. Each machine comes with a comprehensive English Operation Manual and step-by-step installation videos. We also offer remote technical support via video calls. For large-scale production lines, we can arrange for professional engineers to assist with on-site commissioning and staff training.

Answer: * Lead Time: Standard models are typically ready within 15–20 business days. For complex custom projects, the timeline is finalized during the quoting stage.

Packaging: To ensure safe transit, we use heavy-duty, fumigation-free wooden cases that meet international shipping regulations, providing maximum protection against impact and moisture during sea or air freight.

“Still have questions? Contact our technical team for a free consultation.”

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